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Interpersonal-level discrimination indices, sociodemographic factors, and telomere length in African-Americans and Whites.

ABSTRACT: OBJECTIVE:Studies have linked self-reported discrimination to telomere attrition, a biological marker of accelerated cellular aging. However, it is unknown whether intersections between social categories-race, socioeconomic status (SES), sex, and age-influence the association of varying forms of discrimination with telomere length. We examined these associations in a socioeconomically and racially/ethnically diverse urban sample. METHODS:Cross-sectional data were from 341 middle-aged (30-64 years) African American and White, community participants in the Healthy Aging in Neighborhoods of Diversity across the Life Span Study (HANDLS). Multiple regression models examined up to 3-way interactions between a discrimination measure (i.e., everyday, racial, gender, lifetime burden, and frequency of discrimination across sources) and two social categories. RESULTS:After adjusting for depressive symptoms, waist circumference, and lifetime substance use, two themes emerged: 1) among women with higher SES, a) greater lifetime discrimination burden (b = -0.23, p?=? .011), gender discrimination (b = -0.29, p?=? .040), and racial discrimination (b = -0.24, p = 0.023) and 2) among younger adults, irrespective of race and sex, greater frequency of discrimination across sources (b?=?0.002, p?=? .008) was associated with shorter telomeres. CONCLUSIONS:Irrespective of race, women with higher SES and younger adults reporting greater discrimination may be at particular risk for accelerated aging. Telomere attrition promotes and accelerates chronic health conditions for which there are health disparities. Future research explicating intersections among specific discrimination indices and social categories is warranted.

SUBMITTER: Beatty Moody DL

PROVIDER: S-EPMC6438165 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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Interpersonal-level discrimination indices, sociodemographic factors, and telomere length in African-Americans and Whites.

Beatty Moody Danielle L DL Leibel Daniel K DK Darden Taylor M TM Ashe Jason J JJ Waldstein Shari R SR Katzel Leslie I LI Liu Hans B HB Weng Nan-Ping NP Evans Michele K MK Zonderman Alan B AB

Biological psychology 20181213

<h4>Objective</h4>Studies have linked self-reported discrimination to telomere attrition, a biological marker of accelerated cellular aging. However, it is unknown whether intersections between social categories-race, socioeconomic status (SES), sex, and age-influence the association of varying forms of discrimination with telomere length. We examined these associations in a socioeconomically and racially/ethnically diverse urban sample.<h4>Methods</h4>Cross-sectional data were from 341 middle-a ...[more]

PMID: 30553820

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Project description:ObjectivesTo examine whether intersections of race with other key sociodemographic categories contribute to variations in multiple dimensions of race- and non-race-related, interpersonal-level discrimination and burden in urban-dwelling African Americans and Whites.MethodsData from 2,958 participants aged 30-64 in the population-based Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study were used to estimate up to four-way interactions of race, age, gender, and poverty status with reports of racial and everyday discrimination, discrimination across multiple social statuses, and related lifetime discrimination burden in multiple regression models.ResultsWe observed that: 1) African Americans experienced all forms of discrimination more frequently than Whites, but this finding was qualified by interactions of race with age, gender, and/or poverty status; 2) older African Americans, particularly African American men, and African American men living in poverty reported the greatest lifetime discrimination burden; 3) older African Americans reported greater racial discrimination and greater frequency of multiple social status-based discrimination than younger African Americans; 4) African American men reported greater racial and everyday discrimination and a greater frequency of social status discrimination than African American women; and, 5) White women reported greater frequency of discrimination than White men. All p's < .05.ConclusionsWithin African Americans, older, male individuals with lower SES experienced greater racial, lifetime, and multiple social status-based discrimination, but this pattern was not observed in Whites. Among Whites, women reported greater frequency of discrimination across multiple social statuses and other factors (i.e., gender, income, appearance, and health status) than men. Efforts to reduce discrimination-related health disparities should concurrently assess dimensions of interpersonal-level discrimination across multiple sociodemographic categories, while simultaneously considering the broader socioecological context shaping these factors.

Dataset Information

Interpersonal-level discrimination indices, sociodemographic factors, and telomere length in African-Americans and Whites.

Publications

Interpersonal-level discrimination indices, sociodemographic factors, and telomere length in African-Americans and Whites.

Similar Datasets

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