Association of Phenotypic Characteristics and UV Radiation Exposure With Risk of Melanoma on Different Body Sites.

ABSTRACT:

Importance

Two pathways have been hypothesized for the development of cutaneous melanoma: one typically affects the head and neck, a site with chronic sun damage, and the other affects the trunk, which is less exposed to the sun. However, the possible cause of limb melanomas is less studied under this hypothesis.

Objective

To investigate the association between phenotypic characteristics, pattern of UV radiation exposure, and risk of melanoma on different body sites.

Design, setting, and participants

This study used data on 161 540 women with information on phenotypic characteristics and UV radiation exposure who were part of the Norwegian Women and Cancer study, a population-based prospective study established in 1991 with exposure information collected by questionna

SUBMITTER: Ghiasvand R 

PROVIDER: S-EPMC6439571 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature