Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC6445851 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Li Junyi J Yuan Xiucheng X March Michael E ME Yao Xueming X Sun Yan Y Chang Xiao X Hakonarson Hakon H Xia Qianghua Q Meng Xinyi X Li Jin J
Frontiers in genetics 20190327
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease among children which could cause severe disability. Genomic studies have discovered substantial number of risk loci for JIA, however, the mechanism of how these loci affect JIA development is not fully understood. Neutrophil is an important cell type involved in autoimmune diseases. To better understand the biological function of genetic loci in neutrophils during JIA development, we took an integrated multi-omics a ...[more]