Ontology highlight
ABSTRACT:
SUBMITTER: Iglesias V
PROVIDER: S-EPMC6445884 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Iglesias Valentin V Paladin Lisanna L Juan-Blanco Teresa T Pallarès Irantzu I Aloy Patrick P Tosatto Silvio C E SCE Ventura Salvador S
Frontiers in physiology 20190327
Prion-like behavior has been in the spotlight since it was first associated with the onset of mammalian neurodegenerative diseases. However, a growing body of evidence suggests that this mechanism could be behind the regulation of processes such as transcription and translation in multiple species. Here, we perform a stringent computational survey to identify prion-like proteins in the human proteome. We detected 242 candidate polypeptides and computationally assessed their function, protein-pro ...[more]