Ontology highlight
ABSTRACT:
SUBMITTER: Suh SH
PROVIDER: S-EPMC6446200 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Suh Sang Heon SH Choe Kibaek K Hong Seon Pyo SP Jeong Seung-Hwan SH Mäkinen Taija T Kim Kwang Soon KS Alitalo Kari K Surh Charles D CD Koh Gou Young GY Song Joo-Hye JH
EMBO reports 20190219 4
A lacteal is a blunt-ended, long, tube-like lymphatic vessel located in the center of each intestinal villus that provides a unique route for drainage of absorbed lipids from the small intestine. However, key regulators for maintaining lacteal integrity are poorly understood. Here, we explore whether and how the gut microbiota regulates lacteal integrity. Germ depletion by antibiotic treatment triggers lacteal regression during adulthood and delays lacteal maturation during the postnatal period. ...[more]