Ontology highlight
ABSTRACT:
SUBMITTER: Karaffa L
PROVIDER: S-EPMC6447509 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Karaffa Levente L Kubicek Christian P CP
Applied microbiology and biotechnology 20190213 7
Citric acid production by Aspergillus niger and itaconic acid production by Aspergillus terreus are two major examples of technical scale fungal fermentations based on metabolic overflow of primary metabolism. Both organic acids are formed by the same metabolic pathway, but whereas citric acid is the end product in A. niger, A. terreus performs two additional enzymatic steps leading to itaconic acid. Despite of this high similarity, the optimization of the production process and the mechanism an ...[more]