All-Optical Rotational Ultrasound Imaging.

ABSTRACT: Miniaturised high-resolution imaging devices are valuable for guiding minimally invasive procedures such as vascular stent placements. Here, we present all-optical rotational B-mode pulse-echo ultrasound imaging. With this device, ultrasound transmission and reception are performed with light. The all-optical transducer in the probe comprised an optical fibre that delivered pulsed excitation light to an optical head at the distal end with a multi-walled carbon nanotube and polydimethylsiloxane composite coating. This coating was photoacoustically excited to generate a highly directional ultrasound beam perpendicular to the optical fibre axis. A concave Fabry-Pérot cavity at the distal end of an optical fibre, which was interrogated with a tuneable continuous-wave laser, served as an omnidirectional ultrasound receiver. The transmitted ultrasound had a -6 dB bandwidth of 31.3?MHz and a peak-to-peak pressure of 1.87?MPa, as measured at 1.5?mm from the probe. The receiver had a noise equivalent pressure <100?Pa over a 20?MHz bandwidth. With a maximum outer probe diameter of 1.25?mm, the probe provided imaging with an axial resolution better than 50?µm, and a real-time imaging rate of 5 frames per second. To investigate the capabilities of the probe, intraluminal imaging was performed in healthy swine carotid arteries. The results demonstrate that the all-optical probe is viable for clinical rotational ultrasound imaging.

SUBMITTER: Colchester RJ 

PROVIDER: S-EPMC6447544 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature