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Race, Poverty, and Initial Implementation of Precision Medicine for Lung Cancer.


ABSTRACT: Data are limited regarding whether the availability of biomarker-directed therapy for lung cancer exacerbates racial and socioeconomic disparities. Patients diagnosed with stage IV lung adenocarcinoma from 2008 to 2013 were identified using Surveillance, Epidemiology, and End Results Program-Medicare. The primary outcome was a Medicare claim for molecular testing within 60?days of diagnosis, analyzed using multivariable logistic regression; the secondary outcome was overall survival, analyzed using multivariable Cox proportional hazards models. All statistical tests were two-sided. Of 5556 patients, 1437 (25.9%) had molecular testing. Testing rates were 14.1% among black, 26.2% among white, and 32.8% among patients of Asian/other descent (adjusted P?

SUBMITTER: Kehl KL 

PROVIDER: S-EPMC6449167 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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Race, Poverty, and Initial Implementation of Precision Medicine for Lung Cancer.

Kehl Kenneth L KL   Lathan Christopher S CS   Johnson Bruce E BE   Schrag Deborah D  

Journal of the National Cancer Institute 20190401 4


Data are limited regarding whether the availability of biomarker-directed therapy for lung cancer exacerbates racial and socioeconomic disparities. Patients diagnosed with stage IV lung adenocarcinoma from 2008 to 2013 were identified using Surveillance, Epidemiology, and End Results Program-Medicare. The primary outcome was a Medicare claim for molecular testing within 60 days of diagnosis, analyzed using multivariable logistic regression; the secondary outcome was overall survival, analyzed us  ...[more]

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