Ontology highlight
ABSTRACT:
SUBMITTER: Pankov G
PROVIDER: S-EPMC6450526 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Pankov Genady G Dawson Alice A Hunter William N WN
Acta crystallographica. Section F, Structural biology communications 20190313 Pt 4
The thick outer membrane (OM) of Gram-negative bacteria performs an important protective role against hostile environments, supports cell integrity, and contributes to surface adhesion and in some cases also to virulence. A major component of the OM is lipopolysaccharide (LPS), a complex glycolipid attached to a core containing fatty-acyl chains. The assembly and transport of lipid A, the membrane anchor for LPS, to the OM begins when a heteromeric LptB<sub>2</sub>FG protein complex extracts lip ...[more]