Ontology highlight
ABSTRACT:
SUBMITTER: Hoogenboom WS
PROVIDER: S-EPMC6450652 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Hoogenboom Wouter S WS Perlis Roy H RH Smoller Jordan W JW Zeng-Treitler Qing Q Gainer Vivian S VS Murphy Shawn N SN Churchill Susanne E SE Kohane Isaac S IS Shenton Martha E ME Iosifescu Dan V DV
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20120430 2
<h4>Objectives</h4>Treatment-resistant depression is a common clinical occurrence among patients with major depressive disorder (MDD), but its neurobiology is poorly understood. We used data collected as part of routine clinical care to study white matter integrity of the brain's limbic system and its association to treatment response.<h4>Methods</h4>Electronic medical records of multiple large New England hospitals were screened for patients with an MDD billing diagnosis, and natural language p ...[more]