Association and diagnostic value of serum SPINK4 in colorectal cancer.
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ABSTRACT:
SUBMITTER: Xie M
PROVIDER: S-EPMC6451835 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Association and diagnostic value of serum SPINK4 in colorectal cancer.
Xie Mingzhi M Li Kezhi K Li Jilin J Lu Dongcheng D Hu Bangli B
PeerJ 20190404
The role of serum serine peptidase inhibitor, Kazal type 4 (SPINK4), in colorectal cancer (CRC) is largely unknown. This study aimed to explore the association and diagnostic value of serum SPINK4 in CRC. A total of 70 preoperative CRC patients, 30 postoperative CRC patients, 30 gastric cancer patients, and 30 healthy controls were enrolled. Using enzyme-linked immunosorbent assays, we found that the serum SPINK4 level was significantly increased in preoperative CRC compared with postoperative C ...[more]
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