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Comment on "ALK is a therapeutic target for lethal sepsis".


ABSTRACT: Physiologically relevant ALK (anaplastic lymphoma kinase) expression was not detected in human and mouse monocytes and macrophages, suggesting that the effects of bioactive compounds on stimulator of interferon genes (STING) activation may not depend on ALK.

SUBMITTER: Blasco RB 

PROVIDER: S-EPMC6459396 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Comment on "ALK is a therapeutic target for lethal sepsis".

Blasco Rafael B RB   Patrucco Enrico E   Mota Ines I   Tai Wei-Tien WT   Chiarle Roberto R  

Science translational medicine 20181201 471


Physiologically relevant ALK (anaplastic lymphoma kinase) expression was not detected in human and mouse monocytes and macrophages, suggesting that the effects of bioactive compounds on stimulator of interferon genes (STING) activation may not depend on ALK. ...[more]

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