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Obesity hypoventilation syndrome: a current review.


ABSTRACT: Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ? 30 kg/m²) and daytime arterial hypercapnia (PaCO2 ? 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of venous bicarbonate in screening for OHS, and diagnostic criteria for OHS that eliminate the need for polysomnography. In addition, we review advances in the treatment of OHS, including behavioral measures, and recent studies comparing the efficacy of continuous positive airway pressure with that of noninvasive ventilation.

SUBMITTER: Athayde RAB 

PROVIDER: S-EPMC6459748 | biostudies-literature | 2018 Nov-Dec

REPOSITORIES: biostudies-literature

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Obesity hypoventilation syndrome: a current review.

Athayde Rodolfo Augusto Bacelar de RAB   Oliveira Filho José Ricardo Bandeira de JRB   Lorenzi Filho Geraldo G   Genta Pedro Rodrigues PR  

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 20181101 6


Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, w  ...[more]

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