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Skeletal disproportion in glucocorticoid-treated boys with Duchenne muscular dystrophy.

ABSTRACT: We aimed to compare body segment and bone lengths in glucocorticoid-treated boys with Duchenne muscular dystrophy (DMD) with healthy controls using dual-energy absorptiometry (DXA) images. Total height (Ht), sitting height (SH), leg length (LL) and bone lengths (femur, tibia) in boys with DMD and age-matched control boys were measured using DXA. Thirty boys with DMD (median age 10.0 years (6.1, 16.8)) were compared with 30 controls. SH in DMD was 3.3 cm lower (95% CI -?6.1, -?0.66; p?=?0.016). LL in DMD was 7.3 cm lower (95% CI -?11.2, -?3.4; p?

SUBMITTER: Kao KT

PROVIDER: S-EPMC6459782 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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Skeletal disproportion in glucocorticoid-treated boys with Duchenne muscular dystrophy.

Kao Kung-Ting KT Joseph Shuko S Capaldi Nadia N Brown Sarah S Di Marco Marina M Dunne Jennifer J Horrocks Iain I Shepherd Sheila S Ahmed Syed Faisal SF Wong Sze Choong SC

European journal of pediatrics 20190214 5

We aimed to compare body segment and bone lengths in glucocorticoid-treated boys with Duchenne muscular dystrophy (DMD) with healthy controls using dual-energy absorptiometry (DXA) images. Total height (Ht), sitting height (SH), leg length (LL) and bone lengths (femur, tibia) in boys with DMD and age-matched control boys were measured using DXA. Thirty boys with DMD (median age 10.0 years (6.1, 16.8)) were compared with 30 controls. SH in DMD was 3.3 cm lower (95% CI - 6.1, - 0.66; p = 0.016). L ...[more]

PMID: 30762116

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