Ontology highlight
ABSTRACT:
SUBMITTER: Connolly AM
PROVIDER: S-EPMC4305351 | biostudies-other | 2015 Apr
REPOSITORIES: biostudies-other
Connolly Anne M AM Malkus Elizabeth C EC Mendell Jerry R JR Flanigan Kevin M KM Miller J Philip JP Schierbecker Jeanine R JR Siener Catherine A CA Golumbek Paul T PT Zaidman Craig M CM Mcdonald Craig M CM Johnson Linda L Nicorici Alina A Karachunski Peter I PI Day John W JW Kelecic Jason M JM Lowes Linda P LP Alfano Lindsay N LN Darras Basil T BT Kang Peter B PB Quigley Janet J Pasternak Amy E AE Florence Julaine M JM
Muscle & nerve 20150211 4
<h4>Introduction</h4>Therapeutic trials in Duchenne muscular dystrophy (DMD) often exclude non-ambulatory individuals. Here we establish optimal and reliable assessments in a multicenter trial.<h4>Methods</h4>Non-ambulatory boys/men with DMD (N = 91; 16.7 ± 4.5 years of age) were assessed by trained clinical evaluators. Feasibility (percentage completing task) and reliability [intraclass correlation coefficients (ICCs) between morning and afternoon tests] were measured.<h4>Results</h4>Forced vit ...[more]