Long-term outcome of flexible onabotulinum toxin A treatment in facial dystonia.

ABSTRACT:

Purpose

The purpose of this study was to assess the long-term outcome of onabotulinum used to treat facial dystonia and compare a flexible and fixed treatment regimen.

Methods

This was a retrospective comparative study looking at benign essential blepharospasm (BEB), hemifacial spasm (HFS) and aberrant facial nerve regeneration synkinesis (AFR) treatment with onabotulinum toxin A (Botox®) over a minimum of 10 years. Fifty-one patients were recruited into the study, with each dystonia subgroup having 17 patients. Blepharospasm disability score (BDS), subjective improvement score (SIS), duration of maximal effect (DME) and complications were recorded at each visit.

Results

The mean age was 63 years and gender predominately female. Thirty-seven patients underwent flexibl

SUBMITTER: Bladen JC 

PROVIDER: S-EPMC6460690 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature