Ontology highlight
ABSTRACT:
SUBMITTER: Das M
PROVIDER: S-EPMC6461149 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Nucleic acid therapeutics 20181218 2
Nucleic acid-based therapeutics like synthetic small interfering RNAs have been exploited to modulate gene function, taking advantage of RNA interference (RNAi), an evolutionally conserved biological process. Recently, the world's first RNAi drug was approved for a rare genetic disorder in the liver. However, there are significant challenges that need to be resolved before RNAi can be translated in other genetic diseases like cancer. Current drug delivery platforms for therapeutic silencing RNAs ...[more]