Ontology highlight
ABSTRACT:
SUBMITTER: Dong S
PROVIDER: S-EPMC6463490 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Dong Shiyu S Wagner Nicole D ND Russell David H DH
Analytical chemistry 20181001 20
Metallothioneins (MTs) constitute a group of intrinsically disordered proteins that exhibit extreme diversity in structure, biological functionality, and metal ion specificity. Structures of coordinatively saturated metalated MTs have been extensively studied, but very limited structural information for the partially metalated MTs exists. Here, the conformational preferences from partial metalation of rabbit metallothionein-2A (MT) by Cd<sup>2+</sup>, Zn<sup>2+</sup>, and Ag<sup>+</sup> are stud ...[more]