Ontology highlight
ABSTRACT:
SUBMITTER: Li Z
PROVIDER: S-EPMC6467421 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Li Zhixiu Z Akar Servet S Yarkan Handan H Lee Sau Kuen SK Çetin Pınar P Can Gerçek G Kenar Gökce G Çapa Fernur F Pamuk Omer Nuri ON Pehlivan Yavuz Y Cremin Katie K De Guzman Erika E Harris Jessica J Wheeler Lawrie L Jamshidi Ahmadreza A Vojdanian Mahdi M Farhadi Elham E Ahmadzadeh Nooshin N Yüce Zeynep Z Dalkılıç Ediz E Solmaz Dilek D Akın Berrin B Dönmez Salim S Sarı İsmail İ Leo Paul J PJ Kenna Tony J TJ Önen Fatos F Mahmoudi Mahdi M Brown Matthew A MA Akkoc Nurullah N
PLoS genetics 20190404 4
Ankylosing spondylitis (AS) is a highly heritable immune-mediated arthritis common in Turkish and Iranian populations. Familial Mediterranean Fever (FMF) is an autosomal recessive autoinflammatory disease most common in people of Mediterranean origin. MEFV, an FMF-associated gene, is also a candidate gene for AS. We aimed to identify AS susceptibility loci and also examine the association between MEFV and AS in Turkish and Iranian cohorts. We performed genome-wide association studies in 1001 Tur ...[more]