Ontology highlight
ABSTRACT:
SUBMITTER: Al-Salam S
PROVIDER: S-EPMC6468713 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Al-Salam Suhail S Aburawi Elhadi H EH Al-Hammadi Suleiman S Dhanasekaran Sekhar S Shafiuallah Mohamed M Yasin Javed J Sudhadevi Manjusha M Awwad Aktham A Alper Seth L SL Kazzam Elsadig E EE Bellou Abdelouahab A
Biomolecules 20190313 3
Anaphylactic shock (AS) is a life-threatening, multisystem disorder arising from sudden release of mast cell- and basophil-derived mediators into the circulation. In this study, we have used a Wistar rat model to investigate AS-associated histopathologic changes in various organs. Rats were sensitized with ovalbumin (1 mg s.c), and AS was induced by intravenous injection of ovalbumin (1 mg). Experimental groups included nonallergic rats (n = 6) and allergic rats (n = 6). Heart rate and blood pre ...[more]