Ontology highlight
ABSTRACT:
SUBMITTER: Wattenberg BW
PROVIDER: S-EPMC6469711 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Advances in biological regulation 20181123
The myelin sheath, produced by oligodendrocytes in the central nervous system, provides essential electrical insulation to neurons, but also is critical for viability of neurons. Both the protein and lipid composition of this fascinating membrane is unique. Here the focus is on the sphingolipids that are highly abundant in myelin and, in particular, how they are produced. This review discusses how sphingolipid metabolism is regulated. In particular the subcellular localization of lipid metabolic ...[more]