Ontology highlight
ABSTRACT:
SUBMITTER: Cheng L
PROVIDER: S-EPMC6470127 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Cheng Lu L Ramchandran Siddharth S Vatanen Tommi T Lietzén Niina N Lahesmaa Riitta R Vehtari Aki A Lähdesmäki Harri H
Nature communications 20190417 1
Biomedical research typically involves longitudinal study designs where samples from individuals are measured repeatedly over time and the goal is to identify risk factors (covariates) that are associated with an outcome value. General linear mixed effect models are the standard workhorse for statistical analysis of longitudinal data. However, analysis of longitudinal data can be complicated for reasons such as difficulties in modelling correlated outcome values, functional (time-varying) covari ...[more]