Ontology highlight
ABSTRACT:
SUBMITTER: Chen W
PROVIDER: S-EPMC6472429 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Chen Wanze W Schwalie Petra C PC Pankevich Eugenia V EV Gubelmann Carine C Raghav Sunil K SK Dainese Riccardo R Cassano Marco M Imbeault Michael M Jang Suk Min SM Russeil Julie J Delessa Tenagne T Duc Julien J Trono Didier D Wolfrum Christian C Deplancke Bart B
Nature communications 20190418 1
Krüppel-associated box zinc finger proteins (KZFPs) constitute the largest family of mammalian transcription factors, but most remain completely uncharacterized. While initially proposed to primarily repress transposable elements, recent reports have revealed that KFZPs contribute to a wide variety of other biological processes. Using murine and human in vitro and in vivo models, we demonstrate here that one poorly studied KZFP, ZFP30, promotes adipogenesis by directly targeting and activating a ...[more]