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Rasamsonia sp: An emerging infection amongst chronic granulomatous disease patients. A case of disseminated infection by a putatively novel Rasamsonia argillacea species complex involving the heart.

ABSTRACT: Chronic granulomatous disease (CGD) is a heterogeneous condition due to defects in NADPH oxidase characterized by granuloma formation and increased susceptibility to invasive infections, in particular moulds. The use of broad-spectrum, mould-active antifungal prophylaxis has improved mortality. However rare resistant moulds have emerged as important pathogens. Diagnosis of these rare fungi requires molecular techniques, and treatment data are limited. Herein, we present a case of with disseminated Rasamsonia infection involving the heart.

SUBMITTER: Babiker A

PROVIDER: S-EPMC6479014 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Rasamsonia sp: An emerging infection amongst chronic granulomatous disease patients. A case of disseminated infection by a putatively novel Rasamsonia argillacea species complex involving the heart.

Babiker Ahmed A Gupta Nupur N Gibas Connie F C CFC Wiederhold Nathan P NP Sanders Carmita C Mele James J Fan Hongxin H Iovleva Alina A Haidar Ghady G Fernandes Carolyn C

Medical mycology case reports 20190416

Chronic granulomatous disease (CGD) is a heterogeneous condition due to defects in NADPH oxidase characterized by granuloma formation and increased susceptibility to invasive infections, in particular moulds. The use of broad-spectrum, mould-active antifungal prophylaxis has improved mortality. However rare resistant moulds have emerged as important pathogens. Diagnosis of these rare fungi requires molecular techniques, and treatment data are limited. Herein, we present a case of with disseminat ...[more]

PMID: 31032179

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Disseminated Rasamsonia argillacea species complex infections in 8 dogs.

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