Ontology highlight
ABSTRACT:
SUBMITTER: Barbe A
PROVIDER: S-EPMC6479753 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Barbe Alix A Bongrani Alice A Mellouk Namya N Estienne Anthony A Kurowska Patrycja P Grandhaye Jérémy J Elfassy Yaelle Y Levy Rachel R Rak Agnieszka A Froment Pascal P Dupont Joëlle J
International journal of molecular sciences 20190327 7
Adiponectin is the most abundant plasma adipokine. It mainly derives from white adipose tissue and plays a key role in the control of energy metabolism thanks to its insulin-sensitising, anti-inflammatory, and antiatherogenic properties. In vitro and in vivo evidence shows that adiponectin could also be one of the hormones controlling the interaction between energy balance and fertility in several species, including humans. Indeed, its two receptors-AdipoR1 and AdipoR2-are expressed in hypothala ...[more]