Ontology highlight
ABSTRACT:
SUBMITTER: Covey DP
PROVIDER: S-EPMC6481661 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Cell reports 20190401 2
Dopamine (DA) transmission in the nucleus accumbens (NAc) facilitates cue-reward associations and appetitive action. Reward-related accumbal DA release dynamics are traditionally ascribed to ventral tegmental area (VTA) DA neurons. Activation of VTA to NAc DA signaling is thought to reinforce action and transfer reward-related information to predictive cues, allowing cues to guide behavior and elicit dopaminergic activity. Here, we use optogenetics to control DA neuron activity and voltammetry t ...[more]