Direct-acting antivirals for chronic hepatitis C.
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ABSTRACT:
SUBMITTER: Jakobsen JC
PROVIDER: S-EPMC6484376 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Publications
Direct-acting antivirals for chronic hepatitis C.
Jakobsen Janus C JC Nielsen Emil Eik EE Feinberg Joshua J Katakam Kiran Kumar KK Fobian Kristina K Hauser Goran G Poropat Goran G Djurisic Snezana S Weiss Karl Heinz KH Bjelakovic Milica M Bjelakovic Goran G Klingenberg Sarah Louise SL Liu Jian Ping JP Nikolova Dimitrinka D Koretz Ronald L RL Gluud Christian C
The Cochrane database of systematic reviews 20170918
<h4>Background</h4>Millions of people worldwide suffer from hepatitis C, which can lead to severe liver disease, liver cancer, and death. Direct-acting antivirals (DAAs), e.g. sofosbuvir, are relatively new and expensive interventions for chronic hepatitis C, and preliminary results suggest that DAAs may eradicate hepatitis C virus (HCV) from the blood (sustained virological response). Sustained virological response (SVR) is used by investigators and regulatory agencies as a surrogate outcome fo ...[more]
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