Ontology highlight
ABSTRACT:
SUBMITTER: Liu J
PROVIDER: S-EPMC6485219 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Liu Jingwei J Zheng Bowen B Li Ying Y Yuan Yuan Y Xing Chengzhong C
Journal of Cancer 20190223 6
DNA repair systems play a critical role in maintaining the integrity and stability of the genome, which mainly include base excision repair (BER), nucleotide excision repair (NER), mismatch repair (MMR) and double-strand break repair (DSBR). The polymorphisms in different DNA repair genes that are mainly represented by single-nucleotide polymorphisms (SNPs) can potentially modulate the individual DNA repair capacity and therefore exert an impact on individual genetic susceptibility to cancer. Sp ...[more]