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Methotrexate for induction of remission in ulcerative colitis.


ABSTRACT:

SUBMITTER: Chande N 

PROVIDER: S-EPMC6486224 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature

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Methotrexate for induction of remission in ulcerative colitis.

Chande Nilesh N   Wang Yongjun Y   MacDonald John K JK   McDonald John W D JW  

The Cochrane database of systematic reviews 20140827 8


<h4>Background</h4>Ulcerative colitis (UC) is a chronic inflammatory bowel disease. Corticosteroids and 5-aminosalicylates are the most commonly used therapies. However, many patients require immunosuppressive therapy for steroid-refractory and steroid-dependent disease. Methotrexate is a medication that is effective for treating a variety of inflammatory diseases, including Crohn's disease. This review was performed to determine the effectiveness of methotrexate treatment in UC patients. This r  ...[more]

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