Ontology highlight
ABSTRACT:
SUBMITTER: Chande N
PROVIDER: S-EPMC6486224 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Chande Nilesh N Wang Yongjun Y MacDonald John K JK McDonald John W D JW
The Cochrane database of systematic reviews 20140827 8
<h4>Background</h4>Ulcerative colitis (UC) is a chronic inflammatory bowel disease. Corticosteroids and 5-aminosalicylates are the most commonly used therapies. However, many patients require immunosuppressive therapy for steroid-refractory and steroid-dependent disease. Methotrexate is a medication that is effective for treating a variety of inflammatory diseases, including Crohn's disease. This review was performed to determine the effectiveness of methotrexate treatment in UC patients. This r ...[more]