Dataset Information
Etrolizumab for induction of remission in ulcerative colitis.
Ontology highlight
ABSTRACT:
SUBMITTER: Rosenfeld G
PROVIDER: S-EPMC8612697 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Publications
Etrolizumab for induction of remission in ulcerative colitis.
The Cochrane database of systematic reviews 20151202 12
<h4>Background</h4>Etrolizumab (rhuMAb beta7) is an anti-integrin that selectively targets the β7 subunits of the α4β7 and αEβ7 integrins, which are involved in the pathogenesis of ulcerative colitis.<h4>Objectives</h4>The objectives of this review were to assess the efficacy and safety of etrolizumab for induction of remission in ulcerative colitis.<h4>Search methods</h4>We searched PubMed, MEDLINE, EMBASE, and the Cochrane Library (CENTRAL) from inception to 12 March 2015. References and confe ...[more]