The effect of fasting status on lipids, lipoproteins, and inflammatory biomarkers assessed after hospitalization for an acute coronary syndrome: Insights from PROVE IT-TIMI 22.

ABSTRACT:

Background

For decades, fasting for 8 to 12 hours has been recommended for measurement of lipid profiles. The effect of fasting on low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) has been described in healthy cohorts and those with stable disease states. Recently, guidelines suggested that fasting may not be necessary due to its small effect on lipid measures. Little is known, however, regarding whether the impact of fasting is altered in the setting of an acute coronary syndrome (ACS).

Hypothesis

We hypothesized that the post-ACS period would minimally effect the impact of fasting status on lipid measurements.

Methods

We evaluated the association of fasting on lipid and other biomarkers at the randomization visit, which occurred at a median of 7 da

SUBMITTER: Steen DL 

PROVIDER: S-EPMC6489711 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature