Ontology highlight
ABSTRACT:
SUBMITTER: Duxbury EM
PROVIDER: S-EPMC6491035 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Duxbury Elizabeth Ml EM Day Jonathan P JP Maria Vespasiani Davide D Thüringer Yannik Y Tolosana Ignacio I Smith Sophia Cl SC Tagliaferri Lucia L Kamacioglu Altug A Lindsley Imogen I Love Luca L Unckless Robert L RL Jiggins Francis M FM Longdon Ben B
eLife 20190430
It is common to find considerable genetic variation in susceptibility to infection in natural populations. We have investigated whether natural selection increases this variation by testing whether host populations show more genetic variation in susceptibility to pathogens that they naturally encounter than novel pathogens. In a large cross-infection experiment involving four species of <i>Drosophila</i> and four host-specific viruses, we always found greater genetic variation in susceptibility ...[more]