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Anti-vascular endothelial growth factor (VEGF) drugs for treatment of retinopathy of prematurity.


ABSTRACT:

SUBMITTER: Sankar MJ 

PROVIDER: S-EPMC6491066 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature

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Anti-vascular endothelial growth factor (VEGF) drugs for treatment of retinopathy of prematurity.

Sankar Mari Jeeva MJ   Sankar Jhuma J   Chandra Parijat P  

The Cochrane database of systematic reviews 20180108


<h4>Background</h4>Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis in foetal life. Researchers have recently attempted to use anti-VEGF agents for the treatment of retinopathy of prematurity (ROP), a vasoproliferative disorder. The safety and efficacy of these agents in preterm infants with ROP is currently uncertain.<h4>Objectives</h4>To evaluate the efficacy and safety of anti-VEGF drugs when used either as monotherapy, that is without concomitant cryotherapy or lase  ...[more]

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