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Pattern formation and traveling waves in myxobacteria: theory and modeling.

ABSTRACT: Recent experiments have provided new quantitative measurements of the rippling phenomenon in fields of developing myxobacteria cells. These measurements have enabled us to develop a mathematical model for the ripple phenomenon on the basis of the biochemistry of the C-signaling system, whereby individuals signal by direct cell contact. The model quantitatively reproduces all of the experimental observations and illustrates how intracellular dynamics, contact-mediated intercellular communication, and cell motility can coordinate to produce collective behavior. This pattern of waves is qualitatively different from that observed in other social organisms, especially Dictyostelium discoideum, which depend on diffusible morphogens.

SUBMITTER: Igoshin OA

PROVIDER: S-EPMC64958 | biostudies-literature | 2001 Dec

REPOSITORIES: biostudies-literature

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Pattern formation and traveling waves in myxobacteria: theory and modeling.

Igoshin O A OA Mogilner A A Welch R D RD Kaiser D D Oster G G

Proceedings of the National Academy of Sciences of the United States of America 20011201 26

Recent experiments have provided new quantitative measurements of the rippling phenomenon in fields of developing myxobacteria cells. These measurements have enabled us to develop a mathematical model for the ripple phenomenon on the basis of the biochemistry of the C-signaling system, whereby individuals signal by direct cell contact. The model quantitatively reproduces all of the experimental observations and illustrates how intracellular dynamics, contact-mediated intercellular communication, ...[more]

PMID: 11752439

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