Dataset Information

Incidence of dementia after age 90 in a multiracial cohort.

ABSTRACT:

Introduction

Little is known about dementia incidence in diverse populations of oldest-old, the age group with highest dementia incidence.

Methods

Incident dementia diagnoses from 1/1/2010 to 9/30/2015 were abstracted from medical records for 2350 members of an integrated health care system in California (n = 1702 whites, n = 375 blacks, n = 105 Latinos, n = 168 Asians) aged ≥90 in 2010. We estimated race/ethnicity-specific age-adjusted dementia incidence rates and implemented Cox proportional hazards models and Fine and Gray competing risk of death models adjusted for demographics and comorbidities in midlife and late-life.

Results

Dementia incidence rates (n = 771 cases) were lowest among Asians (89.9/1000 person-years), followed by whites (96.9/1000 person-years), Latinos (105.8/1000 person-years), and blacks (121.5/1000 person-years). Cox regression and competing risk models estimated 28% and 36% higher dementia risk for blacks versus whites adjusting for demographics and comorbidities.

Discussion

Patterns of racial/ethnic disparities in dementia seen in younger older adults continue after the age of 90 years, though smaller in magnitude.

SUBMITTER: Gilsanz P

PROVIDER: S-EPMC6497045 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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Publications

Incidence of dementia after age 90 in a multiracial cohort.

Gilsanz Paola P Corrada Maria M MM Kawas Claudia H CH Mayeda Elizabeth Rose ER Glymour M Maria MM Quesenberry Charles P CP Lee Catherine C Whitmer Rachel A RA

Alzheimer's & dementia : the journal of the Alzheimer's Association 20190220 4

<h4>Introduction</h4>Little is known about dementia incidence in diverse populations of oldest-old, the age group with highest dementia incidence.<h4>Methods</h4>Incident dementia diagnoses from 1/1/2010 to 9/30/2015 were abstracted from medical records for 2350 members of an integrated health care system in California (n = 1702 whites, n = 375 blacks, n = 105 Latinos, n = 168 Asians) aged ≥90 in 2010. We estimated race/ethnicity-specific age-adjusted dementia incidence rates and implemented Cox ...[more]

PMID: 30797730

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Dataset Information

Incidence of dementia after age 90 in a multiracial cohort.

Introduction

Methods

Results

Discussion

Publications

Incidence of dementia after age 90 in a multiracial cohort.

Similar Datasets

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