Ontology highlight
ABSTRACT:
SUBMITTER: Lazo EO
PROVIDER: S-EPMC6497106 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Acta crystallographica. Section F, Structural biology communications 20190424 Pt 5
As of 2017, tuberculosis had infected 1.7 billion people (23% of the population of the world) and caused ten million deaths. Mycobacterium tuberculosis (Mtb) is quickly evolving, and new strains are classified as multidrug resistant. Thus, the identification of novel druggable targets is essential to combat the proliferation of these drug-resistant strains. Filamenting temperature-sensitive mutant Z (FtsZ) is a key protein involved in cytokinesis, an important process for Mtb proliferation and v ...[more]