Ontology highlight
ABSTRACT:
SUBMITTER: Chen J
PROVIDER: S-EPMC6500499 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Chen Jie J Jiang Da D Huang Fang F
Zhongguo fei ai za zhi = Chinese journal of lung cancer 20190401 4
In recent years, the checkpoint inhibitors targeted programmed cell death 1 (PD-1) and its ligand 1 (PD-1 ligand, PD-L1) achieved landmark significance in treating a variety of cancers including non-small cell lung cancer (NSCLC). However, current immunotherapy is not precise enough, only 15%-20% of the unselected patients can benefit from the therapy, and there is a possibility of hyperprogression (HP). Therefore, how to select the dominant population is crucial. Although many studies have emph ...[more]