Ontology highlight
ABSTRACT:
SUBMITTER: Yoon S
PROVIDER: S-EPMC6507172 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Yoon Sora S Kim Jinhwan J Kim Seon-Kyu SK Baik Bukyung B Chi Sang-Mun SM Kim Seon-Young SY Nam Dougu D
BMC genomics 20190509 1
<h4>Background</h4>Gene-set analysis (GSA) has been commonly used to identify significantly altered pathways or functions from omics data. However, GSA often yields a long list of gene-sets, necessitating efficient post-processing for improved interpretation. Existing methods cluster the gene-sets based on the extent of their overlap to summarize the GSA results without considering interactions between gene-sets.<h4>Results</h4>Here, we presented a novel network-weighted gene-set clustering that ...[more]