Specimen Pooling as a Diagnostic Strategy for Microbiologic Confirmation in Children with Intrathoracic Tuberculosis.
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ABSTRACT:
SUBMITTER: Walters E
PROVIDER: S-EPMC6509014 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
Specimen Pooling as a Diagnostic Strategy for Microbiologic Confirmation in Children with Intrathoracic Tuberculosis.
Walters Elisabetta E van der Zalm Marieke M MM Demers Anne-Marie AM Whitelaw Andrew A Palmer Megan M Bosch Corné C Draper Heather R HR Schaaf H Simon HS Goussard Pierre P Lombard Carl J CJ Gie Robert P RP Hesseling Anneke C AC
The Pediatric infectious disease journal 20190601 6
Three-hundred four young children with suspected pulmonary tuberculosis had a gastric aspirate, induced sputum and nasopharyngeal aspirate collected on each of 2 consecutive weekdays. Specimens collected on the second day were pooled in the laboratory for each child individually. The diagnostic yield by Xpert and culture from pooled specimens was not significantly different to a single gastric aspirate. ...[more]
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