Ontology highlight
ABSTRACT:
SUBMITTER: Siddique AA
PROVIDER: S-EPMC6511477 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Siddique Arman Alam AA Schnitzer Mireille E ME Bahamyirou Asma A Wang Guanbo G Holtz Timothy H TH Migliori Giovanni B GB Sotgiu Giovanni G Gandhi Neel R NR Vargas Mario H MH Menzies Dick D Benedetti Andrea A
Statistical methods in medical research 20181031 12
This paper investigates different approaches for causal estimation under multiple concurrent medications. Our parameter of interest is the marginal mean counterfactual outcome under different combinations of medications. We explore parametric and non-parametric methods to estimate the generalized propensity score. We then apply three causal estimation approaches (inverse probability of treatment weighting, propensity score adjustment, and targeted maximum likelihood estimation) to estimate the c ...[more]