Nationally-representative serostudy of dengue in Bangladesh allows generalizable disease burden estimates.
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ABSTRACT:
SUBMITTER: Salje H
PROVIDER: S-EPMC6513551 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
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Nationally-representative serostudy of dengue in Bangladesh allows generalizable disease burden estimates.
Salje Henrik H Paul Kishor Kumar KK Paul Repon R Rodriguez-Barraquer Isabel I Rahman Ziaur Z Alam Mohammad Shafiul MS Rahman Mahmadur M Al-Amin Hasan Mohammad HM Heffelfinger James J Gurley Emily E
eLife 20190408
Serostudies are needed to answer generalizable questions on disease risk. However, recruitment is usually biased by age or location. We present a nationally-representative study for dengue from 70 communities in Bangladesh. We collected data on risk factors, trapped mosquitoes and tested serum for IgG. Out of 5866 individuals, 24% had evidence of historic infection, ranging from 3% in the north to >80% in Dhaka. Being male (aOR:1.8, [95%CI:1.5-2.0]) and recent travel (aOR:1.3, [1.1-1.8]) were li ...[more]
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