Independent amylase gene copy number bursts correlate with dietary preferences in mammals.
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ABSTRACT:
SUBMITTER: Pajic P
PROVIDER: S-EPMC6516957 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Publications
Independent amylase gene copy number bursts correlate with dietary preferences in mammals.
Pajic Petar P Pavlidis Pavlos P Dean Kirsten K Neznanova Lubov L Romano Rose-Anne RA Garneau Danielle D Daugherity Erin E Globig Anja A Ruhl Stefan S Gokcumen Omer O
eLife 20190514
The amylase gene (<i>AMY)</i>, which codes for a starch-digesting enzyme in animals, underwent several gene copy number gains in humans (Perry et al., 2007), dogs (Axelsson et al., 2013), and mice (Schibler et al., 1982), possibly along with increased starch consumption during the evolution of these species. Here, we present comprehensive evidence for <i>AMY</i> copy number expansions that independently occurred in several mammalian species which consume diets rich in starch. We also provide cor ...[more]
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