Ontology highlight
ABSTRACT:
SUBMITTER: Fischer P
PROVIDER: S-EPMC6517271 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Fischer Petra P Pogosyan Alek A Green Alexander L AL Aziz Tipu Z TZ Hyam Jonathan J Foltynie Thomas T Limousin Patricia P Zrinzo Ludvic L Samuel Michael M Ashkan Keyoumars K Da Lio Mauro M De Cecco Mariolino M Fornaser Alberto A Brown Peter P Tan Huiling H
Neurobiology of disease 20190306
Beta power suppression in the basal ganglia is stronger during movements that require high force levels and high movement effort but it has been difficult to dissociate the two. We recorded scalp EEG and basal ganglia local field potentials in Parkinson's disease patients (11 STN, 7 GPi) ON and OFF dopaminergic medication while they performed a visually-guided force matching task using a pen on a force-sensitive graphics tablet. Force adjustments were accompanied by beta power suppression irresp ...[more]