Ontology highlight
ABSTRACT:
SUBMITTER: Mollink J
PROVIDER: S-EPMC6517273 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Mollink Jeroen J Smith Stephen M SM Elliott Lloyd T LT Kleinnijenhuis Michiel M Hiemstra Marlies M Alfaro-Almagro Fidel F Marchini Jonathan J van Cappellen van Walsum Anne-Marie AM Jbabdi Saad S Miller Karla L KL
Nature neuroscience 20190415 5
Microscopic features (that is, microstructure) of axons affect neural circuit activity through characteristics such as conduction speed. To what extent axonal microstructure in white matter relates to functional connectivity (synchrony) between brain regions is largely unknown. Using MRI data in 11,354 subjects, we constructed multivariate models that predict functional connectivity of pairs of brain regions from the microstructural signature of white matter pathways that connect them. Microstru ...[more]