Ontology highlight
ABSTRACT:
SUBMITTER: Imdad A
PROVIDER: S-EPMC6517295 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Imdad Aamer A Nicholson Maribeth R MR Tanner-Smith Emily E EE Zackular Joseph P JP Gomez-Duarte Oscar G OG Beaulieu Dawn B DB Acra Sari S
The Cochrane database of systematic reviews 20181113
<h4>Background</h4>Inflammatory bowel disease (IBD) is a chronic, relapsing disease of the gastrointestinal tract that is thought to be associated with a complex interplay between microbes and the immune system, leading to an abnormal inflammatory response in genetically susceptible individuals. Dysbiosis, characterized by the alteration of the composition of the resident commensal bacteria in a host compared to healthy individuals, is thought to play a major role in the pathogenesis of ulcerati ...[more]