Ontology highlight
ABSTRACT:
SUBMITTER: Keller A
PROVIDER: S-EPMC6519740 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Journal of proteome research 20181218 2
In cells, intra- and intermolecular interactions of proteins confer function, and the dynamic modulation of this interactome is critical to meet the changing needs required to support life. Cross-linking and mass spectrometry (XL-MS) enable the detection of both intra- and intermolecular protein interactions in organelles, cells, tissues, and organs. Quantitative XL-MS enables the detection of interactome changes in cells due to environmental, phenotypic, pharmacological, or genetic perturbation ...[more]