Ontology highlight
ABSTRACT:
SUBMITTER: Serrano DR
PROVIDER: S-EPMC6523612 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Serrano Dolores R DR Gordo María José MJ Matji Antonio A González Salvador S Lalatsa Aikaterini A Torrado Juan José JJ
Pharmaceutics 20190404 4
Hydroquinone (HQ) is an anti-hyperpigmentation agent with poor physicochemical stability. HQ formulations are currently elaborated by compounding in local pharmacies. Variability in the characteristics of HQ topical formulations can lead to remarkable differences in terms of their stability, efficacy, and toxicity. Four different semisolid O/W formulations with 5% HQ were prepared using: i) Beeler´s base plus antioxidants (F1), ii) Beeler´s base and dimethyl isosorbide (DMI) as solubiliser (F2), ...[more]