Ontology highlight
ABSTRACT:
SUBMITTER: Kiehart DP
PROVIDER: S-EPMC6524656 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Kiehart Daniel P DP Crawford Janice M JM Aristotelous Andreas A Venakides Stephanos S Edwards Glenn S GS
Annual review of cell and developmental biology 20171001
Dorsal closure is a key process during Drosophila morphogenesis that models cell sheet movements in chordates, including neural tube closure, palate formation, and wound healing. Closure occurs midway through embryogenesis and entails circumferential elongation of lateral epidermal cell sheets that close a dorsal hole filled with amnioserosa cells. Signaling pathways regulate the function of cellular structures and processes, including Actomyosin and microtubule cytoskeletons, cell-cell/cell-mat ...[more]