Ontology highlight
ABSTRACT:
SUBMITTER: Macare C
PROVIDER: S-EPMC6525784 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20180811 10
The TTC12-ANKK1-DRD2 gene-cluster has been implicated in adult smoking. Here, we investigated the contribution of individual genes in the TTC12-ANKK1-DRD2 cluster in smoking and their association with smoking-associated reward processing in adolescence. A meta-analysis of TTC12-ANKK1-DRD2 variants and self-reported smoking behaviours was performed in four European adolescent cohorts (N = 14,084). The minor G-allele of rs2236709, mapping TTC12, was associated with self-reported smoking (p = 5.0 × ...[more]