High fidelity fibre-based physiological sensing deep in tissue.
Ontology highlight
ABSTRACT:
SUBMITTER: Choudhary TR
PROVIDER: S-EPMC6531436 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Publications
High fidelity fibre-based physiological sensing deep in tissue.
Choudhary Tushar R TR Tanner Michael G MG Megia-Fernandez Alicia A Harrington Kerrianne K Wood Harry A HA Marshall Adam A Zhu Patricia P Chankeshwara Sunay V SV Choudhury Debaditya D Monro Graham G Ucuncu Muhammed M Yu Fei F Duncan Rory R RR Thomson Robert R RR Dhaliwal Kevin K Bradley Mark M
Scientific reports 20190522 1
Physiological sensing deep in tissue remains a clinical challenge. Here a flexible miniaturised sensing optrode providing a platform to perform minimally invasive in vivo in situ measurements is reported. Silica microspheres covalently coupled with a high density of ratiometrically configured fluorophores were deposited into etched pits on the distal end of a 150 µm diameter multicore optical fibre. With this platform, photonic measurements of pH and oxygen concentration with high precision in t ...[more]
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